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Description
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Introduction to Fluorescence in Situ Hybridization
Principles and Clinical Applications Edited by Michael Andreeff, M.D.,
PH.D., and Daniel Pinkel, PH.D. Fluorescence In Situ Hybridization
(FISH) has become an essential tool in the diagnosis and management
of a variety of solid tumors and hematologic malignancies in the
clinical setting, as well as an aid in the identification of
particular genetic disorders. Introduction to Fluorescence In Situ
Hybridization provides a solid groundwork in the basic principles and
techniques of FISH and covers in detail the applications of this
technology to cancer in humans, including tumorigenesis, prostate and
breast tumors, myeloid leukemias, and lymphoproliferative
malignancies. The final section of the book is devoted to the
applications of FISH techniques to genetic analysis. This
incorporates radiation biodosimetry in chromosomal aberrations,
genetic toxicology, and multiprobe methods for detecting
chromosomally defective sperm in humans and mice, plus rapid prenatal
diagnosis of chromosomal aneuploidies and detection of fetal trisomy.
Edited by two leading basic and clinical investigators in the field,
with state-of-the-art contributions from expert subspecialists, and
featuring over 200 color illustrations, Introduction to Fluorescence
In Situ Hybridization is an essential reference for clinicians and
investigators in oncology, genetics, and cytometry.
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