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Description
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Cell death is fast becoming one of the most dynamic areas of
biological research-involving as it does the study of apoptosis and
programmed cell death and the role these phenomena play in development
and homeostasis on the one hand, and aging and disease on the other. The
profound implications for medicine and agriculture from the manipulation
of these processes have spawned a deluge of research papers, articles,
approaches, and methods-making it difficult for scientists to get an
overview of the field.
When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed
Cell Death offers the most thorough, cutting-edge coverage of this field
since publication of the acclaimed first edition. Leading international
researchers present an up-to-date yet accessible survey ranging from the
history of cell death science to its modern methodology. Extensively
revised to include major advances in research, this new edition features
relevant discussion of:
* The impact of genomics and proteomics
* Gene therapy and pharmacogenetics
* The role of mitochondria
* Caspase-independent and non-apoptotic cell death
* Evolution of mechanisms
With the manipulation of programmed cell death in clinical situations now
in the foreseeable future, When Cells Die II also addresses the role of
apoptosis in specific organ systems-the immune system, nervous system,
and gastrointestinal tract-as well as different disease states, including
viral infection, cancer, and myocardial infarct.
Expertly edited to provide detailed cross-referencing, consistency of
style, and a logical progression of topics, When Cells Die II is the
definitive resource for understanding current cell death science. It will
prove an invaluable text for advanced undergraduate, graduate, and
medical students, postdoctoral fellows, scientists, and clinicians in
cell biology, immunology, developmental biology, neuroscience, and cancer
research.
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